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KMID : 0363420020160010021
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Journal of Korean Oriental Pediatrics
2002 Volume.16 No. 1 p.21 ~ p.37
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Effect of Sunbangpaedoktang on the Cytokine Secretory Function of Monocyte Isolated and Cultured from Peripheral Blood of AD Patients
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Shin Dong-Gil
Lee Jin-Yong
Kim Deog-Gon
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Abstract
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Effect of Sunbangpaedoktang, which has been used for atopic dermatitis(AD), on the cytokine secretory function of monocyte, which was isolated and cultured from peripheral blood of AD patients, were evaluated. The results were as follows: 1. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on IL-4. 2. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on IL-5(p<0.05). 3. In AD patients, Sunbangpaedoktang exhibits statistically significant inhibitory effect on $IFN-{\gamma}$(p<0.01). 4. In sample group, comparing the cytokine concentration change rate of AD patients with that of NAD patients IL-4 AD patients exhibits statistically significant decrease(p<0.05).
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KEYWORD
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Sunbangpaedoktang, cytokine, atopic dermatitis
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